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#1
01-05-2007, 01:42 PM
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Permax believed to cause Heart Valve Damage
This just hit the news yesterday. It's sort of scary. I take Mirapex which is in a similar catagory as Permax but they don't mention Mirapex in the article below. Has anyone heard if Mirapex can cause heart damage?
Ashley http://www.webmd.com/content/article/131/117959.htm Jan. 3, 2007 -- Two drugs used in the treatment of Parkinson's disease Parkinson's disease appear to increase the risk of heart valve disease, according to new research that also raises safety questions about similar-acting drugs. The drugs pergolide, marketed as Permax, and cabergoline, sold as Dostinex, were associated with heart valve damage in two European studies published in the Jan. 4 issue of the New England Journal of Medicine. Both drugs are in a class known as ergot-derived dopamine receptor agonists, and both have been linked to heart valve issues in earlier case reports. 
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