Ted Hutchinson
11-03-2009, 05:01 PM
Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity (http://ow.ly/xInT)The objective of the present study was to investigate the relationship between plasma n-3 PUFA composition and weight status.
A total of 124 adults, stratified by weight status:
healthy weight (n 21),
overweight (n 40) and
obese (n 63) were recruited.
Fasting blood samples, anthropometric measures and body composition were collected.
Plasma fatty acid composition was determined by GC.
BMI, waist circumference and hip circumference were inversely correlated with n-3 PUFA, EPA and DHA (P < 0·05 for all) in the obese group.
Obese individuals had significantly lower plasma concentrations of total n-3 PUFA, compared with healthy-weight individuals (4·53 (sd 1·11) v. 5·25 (sd 1·43) %).
When subjects were pooled and stratified into quartiles of total n-3 PUFA, a significant inverse trend was found for BMI (P = 0·002), waist circumference and hip circumference (P = 0·01 and P < 0·001 respectively).
Higher plasma levels of total n-3 PUFA are associated with a healthier BMI, waist circumference and hip circumference.
Our findings suggest that n-3 PUFA may play an important role in weight status and abdominal adiposity.
Omega 3 , as also does vitamin D3, upregulates adiponectin levels.
adiponectin (http://nephropal.blogspot.com/2009/11/curcumin-curry-and-adiponectin.html)
improves insulin sensitivity but also:
reduces liver glucose production
increases glucose uptake in the muscles and adipose tissues
causes oxidation of fats which leads to less lipid production
has anti-inflammatory properties
protects the heart against ischemia and reduces myocardial infarct size
acts as an anti-clotting factor
increases nitric oxide production in the vasculature leading to a greater dilation of the vessels.
So not only should people who are obese take more omega 3 (and Vitamin D3) because their bodies have more use for it BUT also increasing omega 3 levels will lead to improved satiety levels and thus reduce hunger pangs and the need to eat. Low omega 3 (& vitamin D3) levels not only are found in obese /overweight people but also part of the cause of remaining overweight.
A total of 124 adults, stratified by weight status:
healthy weight (n 21),
overweight (n 40) and
obese (n 63) were recruited.
Fasting blood samples, anthropometric measures and body composition were collected.
Plasma fatty acid composition was determined by GC.
BMI, waist circumference and hip circumference were inversely correlated with n-3 PUFA, EPA and DHA (P < 0·05 for all) in the obese group.
Obese individuals had significantly lower plasma concentrations of total n-3 PUFA, compared with healthy-weight individuals (4·53 (sd 1·11) v. 5·25 (sd 1·43) %).
When subjects were pooled and stratified into quartiles of total n-3 PUFA, a significant inverse trend was found for BMI (P = 0·002), waist circumference and hip circumference (P = 0·01 and P < 0·001 respectively).
Higher plasma levels of total n-3 PUFA are associated with a healthier BMI, waist circumference and hip circumference.
Our findings suggest that n-3 PUFA may play an important role in weight status and abdominal adiposity.
Omega 3 , as also does vitamin D3, upregulates adiponectin levels.
adiponectin (http://nephropal.blogspot.com/2009/11/curcumin-curry-and-adiponectin.html)
improves insulin sensitivity but also:
reduces liver glucose production
increases glucose uptake in the muscles and adipose tissues
causes oxidation of fats which leads to less lipid production
has anti-inflammatory properties
protects the heart against ischemia and reduces myocardial infarct size
acts as an anti-clotting factor
increases nitric oxide production in the vasculature leading to a greater dilation of the vessels.
So not only should people who are obese take more omega 3 (and Vitamin D3) because their bodies have more use for it BUT also increasing omega 3 levels will lead to improved satiety levels and thus reduce hunger pangs and the need to eat. Low omega 3 (& vitamin D3) levels not only are found in obese /overweight people but also part of the cause of remaining overweight.