Dan Burdick
11-26-2006, 06:22 PM
They finally find a receptor site for an unusual hallucinogen called Salvia, and immediately propose creating a blocking drug agent for use in socalled "schizophrenia." What cheesy frauds the psychopharmacologist doctors. :rolleyes:
Originally posted 10-10-2005.
Like to complain again about a technical topic area where other's fear to tread. A little something I've been working with here before, which my fans may recognize. (Either one - - or Both.)
The hideously brilliant and technical chemical developmental research involved
in their (super scientific) reseachers looking for the new wonder drugs.
One look at that level of the proceedings and we may be inclined to step back in reverent awe. That's part of their program, well, you know... ****... if they can handle developmental-organic-chemisry, then How can We possibly criticise their selling us (rat poison) their products?
Here's my little topic area again-
They're working on a schizophrenia treatment (in actuality, read that instead: new patent drug they can make money with.)
I was looking around, on the computer,
at stuff on the internet about
seritonin
agonists (that is,stimulator drugs)
and antagonists (depressor/blocker drugs.) Looking at stuff on halucinogenic drugs.
There's this one type of seritonin receptor type called 5HT2a (Seritonin 2a). The researchers determined that certain, partcular psychedelic drugs are 5HT2a agonists.
Pretty cool. They can tell that certain hallucinogenic drugs stimulate 5HT2a. Way to go organic-chemistry-brain researchers! Reverent awe!
Well that's IT. Good enough research right there! Psychopharm researchers for A.P.A. psychiatry could immediately turn that factoid around to their benefit! Good enough for Psychopharm!! All they had Now to do was cook up antagonists for 5HT2a, and announce what steller researchers they were; that they had come up with a New wonder drug based upon modern biochemical scientific research.
{ from a google search for "zyprexa risperidal 5HT2a D2," http://sorrel.humboldt.edu/~morgan/schiz_05.htm "Advanced Psychopharmacology Spring, 2005" In the section entitled EMPIRICAL RESEARCH
note the dose of haloperidol. Note, in their safety and efficacy tests, the drug dose of Haloperidol they employ when using it as the old-drug standard comparison to the new drug under study: "20 mg of haloperidol." This is not so much in the way of being the optimal dose as being a, deleterious, maximal dose. See for instance http://www.mentalhealth.com/mag1/p5m-sc03.html and http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract } {also consider that patients given placebo would probably be in heavy neuroleptic withdrawal, "extrapyramidal side effects was no greater in patients receiving 6 mg of risperidone than in patients receiving placebo," and that if they were comparing these drugs to Haloperidol at 20mg and finding that they had a superior ability to "treat negative symptoms," that haloperidol at a 20-mg dose causes people to deteriorate significantly with regard to Brief Psychiatric Rating Scale ratings of Withdrawal-Retardation: blunted affect, motor retardation, and emotional withdrawal. (see above, the 3rd URL) }
So their new wonder drugs risperidal (Ratsperishedall) and zyprexa (ZyclonXedya)
new wonder drugs
don't merely block dopamine 2 (as the old wonder drugs did
..for the last 50 years, of sales, to the needful sick people - bless them one and all! the humanitarian savants!...
They block seritonin 2A receptors as well !!
{And that's not all. They used their expertise to design for other deep thought considerations as well. Equally suffiscated. So these drugs are too too modern. They could not used-to-have-dealt with these deep questions & ideas and matters three decades ago - new technical capabilities...}
__________________________________________________ ____________
Some (other) researchers developed some work and said: Look! These psychedilic drugs are 5ht2a receptor agonists!
And the drug companies chemists said - we can play that game!
We can make somethings to clog those receptors. Voila - cutting edge new "antipsychotic" medicine developmental research.
__________________________________________________ ______________
Anyway I just saw this same topic again. (Halucinogen information being used by the Folks of the Psychopharm Fraud as a bogus scientific pretence for clogging neuroreceptors in the guise of creating a new faux specific treatment.) Up till recently we did not know, at all, what the powerful Sativa Divinorum did. This unique Sacred divination plant was diferent from all the others.
I just saw that they had "a breakthough on the Sativa Divinorum front," so to speak, they have just found and described an associated, unusual, receptor site where it is in some manner an agonist.
http://scholar.google.com/scholar?hl...allucinogen +
Previous above URL not known now due to memory crash. See: http://www.pnas.org/cgi/content/abstract/182234399
__________________________________________________ ___________
We are told, that they are thinking of antagonists for this receptor site,
part of cutting edge "antipsychotic" "medicine" research.
__________________________________________________ ___________
Genius!! Simply Genius at work. Such humanitarians! Bless them for their Brilliant thinking and their Altruistic motives! Bless the Rockefeller Foundation, and Harvard too. (Take your meds now, Tiny Tim.)
http://scholar.google.com/scholar?hl=en&lr=&sa=X&oi=scholart&q=Sheffler+et+al,+Salvinorin+A:+the+%22magic+mint% 22+hallucinogen+
Originally posted 10-10-2005.
Like to complain again about a technical topic area where other's fear to tread. A little something I've been working with here before, which my fans may recognize. (Either one - - or Both.)
The hideously brilliant and technical chemical developmental research involved
in their (super scientific) reseachers looking for the new wonder drugs.
One look at that level of the proceedings and we may be inclined to step back in reverent awe. That's part of their program, well, you know... ****... if they can handle developmental-organic-chemisry, then How can We possibly criticise their selling us (rat poison) their products?
Here's my little topic area again-
They're working on a schizophrenia treatment (in actuality, read that instead: new patent drug they can make money with.)
I was looking around, on the computer,
at stuff on the internet about
seritonin
agonists (that is,stimulator drugs)
and antagonists (depressor/blocker drugs.) Looking at stuff on halucinogenic drugs.
There's this one type of seritonin receptor type called 5HT2a (Seritonin 2a). The researchers determined that certain, partcular psychedelic drugs are 5HT2a agonists.
Pretty cool. They can tell that certain hallucinogenic drugs stimulate 5HT2a. Way to go organic-chemistry-brain researchers! Reverent awe!
Well that's IT. Good enough research right there! Psychopharm researchers for A.P.A. psychiatry could immediately turn that factoid around to their benefit! Good enough for Psychopharm!! All they had Now to do was cook up antagonists for 5HT2a, and announce what steller researchers they were; that they had come up with a New wonder drug based upon modern biochemical scientific research.
{ from a google search for "zyprexa risperidal 5HT2a D2," http://sorrel.humboldt.edu/~morgan/schiz_05.htm "Advanced Psychopharmacology Spring, 2005" In the section entitled EMPIRICAL RESEARCH
note the dose of haloperidol. Note, in their safety and efficacy tests, the drug dose of Haloperidol they employ when using it as the old-drug standard comparison to the new drug under study: "20 mg of haloperidol." This is not so much in the way of being the optimal dose as being a, deleterious, maximal dose. See for instance http://www.mentalhealth.com/mag1/p5m-sc03.html and http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract } {also consider that patients given placebo would probably be in heavy neuroleptic withdrawal, "extrapyramidal side effects was no greater in patients receiving 6 mg of risperidone than in patients receiving placebo," and that if they were comparing these drugs to Haloperidol at 20mg and finding that they had a superior ability to "treat negative symptoms," that haloperidol at a 20-mg dose causes people to deteriorate significantly with regard to Brief Psychiatric Rating Scale ratings of Withdrawal-Retardation: blunted affect, motor retardation, and emotional withdrawal. (see above, the 3rd URL) }
So their new wonder drugs risperidal (Ratsperishedall) and zyprexa (ZyclonXedya)
new wonder drugs
don't merely block dopamine 2 (as the old wonder drugs did
..for the last 50 years, of sales, to the needful sick people - bless them one and all! the humanitarian savants!...
They block seritonin 2A receptors as well !!
{And that's not all. They used their expertise to design for other deep thought considerations as well. Equally suffiscated. So these drugs are too too modern. They could not used-to-have-dealt with these deep questions & ideas and matters three decades ago - new technical capabilities...}
__________________________________________________ ____________
Some (other) researchers developed some work and said: Look! These psychedilic drugs are 5ht2a receptor agonists!
And the drug companies chemists said - we can play that game!
We can make somethings to clog those receptors. Voila - cutting edge new "antipsychotic" medicine developmental research.
__________________________________________________ ______________
Anyway I just saw this same topic again. (Halucinogen information being used by the Folks of the Psychopharm Fraud as a bogus scientific pretence for clogging neuroreceptors in the guise of creating a new faux specific treatment.) Up till recently we did not know, at all, what the powerful Sativa Divinorum did. This unique Sacred divination plant was diferent from all the others.
I just saw that they had "a breakthough on the Sativa Divinorum front," so to speak, they have just found and described an associated, unusual, receptor site where it is in some manner an agonist.
http://scholar.google.com/scholar?hl...allucinogen +
Previous above URL not known now due to memory crash. See: http://www.pnas.org/cgi/content/abstract/182234399
__________________________________________________ ___________
We are told, that they are thinking of antagonists for this receptor site,
part of cutting edge "antipsychotic" "medicine" research.
__________________________________________________ ___________
Genius!! Simply Genius at work. Such humanitarians! Bless them for their Brilliant thinking and their Altruistic motives! Bless the Rockefeller Foundation, and Harvard too. (Take your meds now, Tiny Tim.)
http://scholar.google.com/scholar?hl=en&lr=&sa=X&oi=scholart&q=Sheffler+et+al,+Salvinorin+A:+the+%22magic+mint% 22+hallucinogen+