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View Full Version : Multiple sclerosis research may speed up with new mouse model of disease


squiffy2
11-06-2008, 03:46 AM
http://www.msrc.co.uk/images/gallery/img_myelin.jpg
A new study highlights the role of a charge-switching enzyme in nervous system deficits characteristic of multiple sclerosis and other related neurological illness.

Multiple sclerosis (MS) is one of several diseases in which myelin - the insulator for electrical signaling in the nervous system - breaks down and causes severe deficits in brain and nerve function. Much like the rubber insulation on an electrical cord, myelin surrounds long projections from the body of a neuron, and allows signals to travel down the cell with speed and efficiency. Patients with MS and other "de-myelinating" diseases therefore suffer deficits in balance, coordination, and movement, as well as sensory disturbances, from the loss of this neuronal insulation.

A major research initiative in treating these diseases is identifying the molecular factors and changes that lead to myelin breakdown.

In a new study published in Disease Models & Mechanisms a team of Canadian researchers report on a new mouse model of disease which will help in understanding how demyelination occurs.......................................

For the full report please go to MSRC: MS Research News : Myelin Research (http://www.msrc.co.uk/index.cfm?fuseaction=show&pageid=1845)