Problems with Avandia

[annelb]

In January 2006 the FDA warned of macular edema with the use of Avandia. http://www.fda.gov/medwatch/safety/2006/safety06.htm#Avandia

Then there was an alert on increased risk of fracture with Avandia http://www.fda.gov/medwatch/safety/2007/safety07.htm#rosiglitazone

Now there is an alert about a possible connection between Avandia and heart attack http://www.fda.gov/bbs/topics/NEWS/2007/NEW01636.html

Anne

[annelb]

A black box waring has been added to Avandia and Actos.
Both Avandia and ACTOS have been asked to add "black box" warnings on their labels while the FDA continues to investigate. On July 30, 2007, the FDA's Endocrinologic and Metabolic Drugs Advisory Committee and Drug Safety and Risk Management Advisory Committee will meet to discuss the cardiovascular ischemic and thrombotic (heart-related) risks of thiazolidinediones, focusing particularly on rosiglitazone (Avandia).


http://www.medadnews.com/News/index.cfm?articleid=458149
Anne